The truth is, except for a small number of special cases (final boss, Quarian crash site N7 mission), ME2's enemies do not respawn infinitely. ![]() Infinite respawns: This is a misperception about the game. The Avalanche is helpful against husks, and definitely bring the Cain for the final boss fight. Heavy weapon: I didn't use heavy weapons a ton, but I've found that the Arc Projector is generally the most useful, especially against tightly packed groups of mercs. Assault rifles are much less valuable since the Locust SMG was added to the game, and the shotgun is just a poor choice on Insanity because 99% of the time, you're going to want to stay in cover as far away from the enemies as possible. Being able to hang way back and hurt enemies from afar is an incredibly valuable thing on Insanity. Weapons training: In my mind, the sniper rifle is definitely the way to go. Squadmates will do more damage with the Tempest however. The Locust is by far the best SMG for Shepard and practically makes assault rifles redundant. The Locust SMG and extra Tech Damage upgrade are incredibly valuable, especially in the very early game. Kasumi: Do Kasumi's loyalty mission as soon as possible if you are any class except Soldier or possibly Vanguard. A lot of people recommend the various defensive powers but I feel that as long as you use cover effectively, extra damage is a lot more valuable than extra survivability. Squad Armor Piercing Ammo and Squad Warp Ammo are both good choices. Legion, Garrus, and Mordin can also be valuable in certain circumstances, but when in doubt, Zaeed, Grunt, and Thane are your go-to guys for the third squad member.īonus power: I personally feel that ammo powers are the way to go since the others tend to be quite situational. Other generally good choices are Grunt for his very high survivability and Squad Incendiary Ammo for missions with vorcha or krogan enemies, and Zaeed for his Squad Disruptor Ammo, sniper rifle skill, and very high damage output. This makes Thane a good choice, especially on missions with Collectors. Biotic squadmates are generally not very helpful since practically every single enemy will have shielding, armor, or both- with the exception of biotics with the Warp ability. In general, teammates with sniper rifles are very valuable and teammates with shotguns will just rush the enemies and get themselves killed (Grunt is an exception because of his exceptionally high health). The other squadmate is somewhat situational. With Warp, Overload, 15% squad weapon damage bonus, and decent survivability, no one else touches her. Squadmates: Miranda is mandatory for every mission. ![]() There's a lot of advice here already, and much of it comes down to what personally works for you and your playstyle, but I'll share a few things that helped me with an Engineer Insanity playthrough.
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